Composition:
Each gm contains:
Lincomycin hydrochloride H2O ………470.6 mg
( Corr. Lincomycin 415 mg)
Properties:
Lincomycin is a lincosamides antibiotic produced by Streptomyces lincolensis. Lincomycin is bacteriostatic in action inhibiting the protein synthesis predominantly by binding to the 50S ribosomal subunits of bacteria.
Depending on the sensitivity of micro-organisms, and on the concentration of the active substance, the protein synthesis inhibition antibacterial action can either be bacteriostatic or bactericide.
Lincomycin is active against:
- Wide range of Gram-positive bacteria, such as staphylococci, streptococci, β-haemolytic streptococci, corynebacteria, Erysipelothrix spp.,
- Anaerobic bacteria, such as clostridia, Bacteroides spp., Brachyspira spp., as well as Leptospira spp. and Mycoplasma spp.
- Lincomycin has no activity against Gram-negative bacteria, such as Klebsiella spp., Pasteurella spp., and Salmonella spp.
The resistance rate against Lincomycin is slow.
Indications:
Broiler chickens:
For treatment of necrotic enteritis caused by Clostridium perfringens.
Pigs:
For treatment of Swine dysentery, mycoplasma pneumonia caused by Mycoplasma hyopneumoniae.
Target species:
Broiler chicken
Pigs
Dosage& Route of administration:
Route of administration: orally via drinking water.
For whole product:
Broiler chicken:
1 gm Globalinc / 8.3 liter of drinking water, for 7 days.
Pigs:
1gm Globalinc/ 41.5 kg of body weight, for 10 days.
Warning Precaution:
Don’t use in pregnant animal.
Don’t use in animal producing milk.
Don’t use with novobiocin , kanamycin, macrolides and lincosamide.
Contra –Indication:
Don’t use in horse, gunea pigs, hamster and rabbits.
Don’t use in known hypersensitivity to lincomycin.
Side Effects:
In pigs: Lincomycin has a good margin of safety, but higher levels of dosage than recommended may cause diarrhoea and loose stools in pigs.
In broiler chicken:
- Not reported in recommended dose.
- May cause GIT disturbance.
Withdrawal time:
Broiler chicken:
Meat: 5 days.
Pigs: 0 days.
Storage:
Stored at temperature not exceeding 30ْ c, in dry place and used immediately after opening and reconstitution.
Packs:
White plastic (HDPE) jar containing 150 gm water soluble powder .
