Composition:
Each 100 gm contains:
Colistin Sulphate ……………………………………………………..600 million IU.
Properties:
Colistin is a bactericidal polypeptide antibiotic belongs to polymyxin group. It produces its antibacterial effect by interacting strongly with phospholipids in bacterial cell membrane & radically disturbed their permeability & function.
Colistin is active against gm -ve bacteria including E.coli & salmonella spp.
Indications:
Royal Colistin is indicated for treating Coli-enteritis and Enteritis caused by Gram-negative bacteria, particularly E-coli, Pseudomonas spp. Klebsiella spp. And Salmonella spp, In Poultry, Rabbits, Calves, Sheep and Goats.
Dosage & Route of administration:
Poultry: 1gm / 6 liter of drinking water daily for 4-5 successive days.
Rabbits: 0.5 gm / 25 kg b. w. daily for 4-5 successive days.
Calves, Sheep & Goats: 40000 IU / kg b.w. for 3-5 successive days
Withdrawal period:
Meat: 7 days.
Poultry: 3 days.
Contra-indication.
-not be used in animal hypersensitive to colistin.
-not be used in animal with renal failure.
-not be used with cations (calcium, magnesium, manganese) and unsaturated fatty acids as colistin antagonized with them.
Side effects:
No side effect in the recommended dose but in case of overdose digestive problems may occur such as a transient softening of feces or bloat.
Storage:
Store in a cool dray place and protected from light within tightly closed container.
Packaging:
(HDPE) plastic container 100gm
